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วันศุกร์ที่ 8 มิถุนายน พ.ศ. 2555

Man's Head Reshaped With Fat From His Stomach

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Main Category: Cosmetic Medicine / Plastic Surgery
Article Date: 01 Mar 2012 - 0:00 PST Current ratings for:
'Man's Head Reshaped With Fat From His Stomach'
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Hang onto that belly fat, it may come in useful! In a UK first, surgeons at King's College Hospital in London, have taken fat from a man's stomach and injected it into his head to help reshape it. The patient had had some of his skull removed, and surgery to reconstruct a shattered eye socket, cheekbone, and leg, following injuries sustained when he fell while climbing up a drainpipe outside his house.

The patient is Tim Barter, a visual effects supervisor on the Dr Who television series. In June 2009, Barter, then 32, fell 25 ft (over 7.5 m) off a drainpipe onto a brick wall as he tried to gain entry into his house in Brixton, through an upstairs window. He had lost his keys the night before on a night out.

His neighbours found him a short while later, and he was taken by ambulance to the Major Trauma Centre at King's College Hospital.

Barter was in a coma for 10 days. When he woke up, he discovered he had a brain haemorrhage, a shattered eye socket, cheekbone, and a broken leg.

Barter says he does not remember the fall at all. He says he probably broke his leg when he fell onto a brick wall that temporarily broke his fall, and then must have landed on his face after he carried on falling.

Rob Bentley, a Craniofacial Surgeon at King's, told Barter that to ease the swelling in his brain from the haemorrhage, they had removed part of his skull.

Barter learned that he would also need further surgery to reconstruct his cheekbone, eye socket and leg.

In a statement released from King's this week, he says:

"My head felt really strange. I only had skin over where the skull had been removed so it was very soft to touch, particularly when the hair had started to grow back."

Barter was in hospital for several weeks, while he had titanium plates fitted to shape his shattered eye socket and hold the bone together. These were inserted through his mouth so as not to leave scars on his face.

He then went home, but couldn't go outside much: doctors told him to stay indoors to rest and repair. Barter was worried that he would not be able to work again.

"Life stopped for a number of months. I couldn't work and I had double vision. I was frightened that my eyesight would never go back to normal and that I would have to give up my job for good," he said.

Eventually, in December 2009, some six months after his fall, surgeons at King's fitted a titanium plate to replace the removed piece of skull in Barter's head.

Up until having the plate fitted, simple things like going to the toilet gave him intense headaches, explained Barter, "Bending down to do anything was agony," he said.

Experts at King's had made the plate from a mirror image of the other side of Barter's skull, modelled using computer technology.

Bentley, who is also Director of Trauma, said:

"Tim came to us with significant head and facial injuries and was treated here both in the initial phases and also for his secondary reconstruction."

He explained that Barter's case highlights an area of expertise that he has developed at King's over the last nine years, during which time they have inserted over 250 such prostheses with the lowest infection rates in the world.

Later, the surgeons then also took fat from Barter's stomach and injected it into his temple to fill a hole that had appeared when some inactive muscle collapsed.

This is the first time a patient has undergone such a procedure in the UK.

Bentley and his team at King's developed the new and unique cosmetic technique to restore the face after injury.

Since the surgery, Barter has completely changed his life. He is keeping fit (he sees a personal trainer four times a week), is improving his diet (he has consulted a nutritionist), has had his teeth reconstructed and his eyes lasered so he does not have to wear glasses.

And the trauma of the fall has not put him off heights: if anything it has given him a love of tough sports, including sky-diving, rock climbing, fencing and kayaking.

He says he is now "simply making the most of everything" and even loves the sensation of falling in the extreme sports he is practising, and jokes that the "split second" at the end is only "an occasional problem".

Bentley and his patient Barter, will be talking about the methods used at King's to repair Barter's injuries on BBC Breakfast at 08:10 am on Thursday 1 March.

Written by Catharine Paddock PhD
Copyright: Medical News Today
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Catharine Paddock PhD. "Man's Head Reshaped With Fat From His Stomach." Medical News Today. MediLexicon, Intl., 1 Mar. 2012. Web.
8 Jun. 2012. APA

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Publication Of Cytori Breast Reconstruction Cell Therapy Trial Results

Main Category: Breast Cancer
Also Included In: Cosmetic Medicine / Plastic Surgery
Article Date: 21 Mar 2012 - 0:00 PDT
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Cytori Therapeutics (NASDAQ: CYTX) has announced the publication of RESTORE-2 trial results in the peer-reviewed European Journal of Surgical Oncology.

RESTORE-2 is a 71 patient multi-center, prospective clinical trial using autologous adipose-derived regenerative cell (ADRC)-enriched fat grafting for reconstruction of the breast after cancer surgery. The majority of patients underwent radiation prior to the procedure, creating an unfavorable ischemic environment for which breast reconstruction with ADRC-enriched fat grafting appears to be ideally suited.

Key findings of the trial were: High rates of investigator (85%) and patient (75%) satisfaction with the overall treatment results at 12 months; High rates of investigator (87%) and patient (67%) satisfaction with overall breast deformity (based on functional and cosmetic outcomes) at 12 months; Improved breast contour at both six and 12 months, demonstrated by blinded MRI assessment; and No local cancer recurrences or serious adverse events related to the ADRC-enriched fat grafting procedure. "Following cancer treatment, the patient's breast tissue can suffer from radiation injury, scarring and tight skin," said Consultant Plastic and Reconstructive Surgeon Mrs. Eva Weiler-Mithoff, co-principal investigator for RESTORE-2 at the NHS Glasgow Royal Infirmary Hospital. "This new technique is exciting because it may offer the opportunity to resolve some of the most difficult to treat conditions where other approaches, including fat alone, do not achieve satisfactory results."

ADRC-enriched partial mastectomy breast reconstruction is marketed in the EU as the RESTORE Procedure and represents an innovative treatment option with significant cost savings potential. The procedure can be performed on an outpatient basis. Satisfactory results can be achieved in a single procedure for the majority of patients. In contrast, competitive approaches are more costly with lengthy hospital stays, require repeat procedures and increase the overall burden on the healthcare system. Furthermore, because of these limitations, physicians are often reluctant to recommend reconstruction for patients with partial mastectomy defects and radiation-induced damage in the breast.

Each year, approximately 450,000 European women are diagnosed with breast cancer. Of the newly diagnosed breast cancer cases, 70-80% are eligible for breast conserving surgery, where only a portion of the breast is removed rather than the full breast. In the European G5, there are an estimated 1.25 million women who have undergone partial mastectomy. The majority of these patients are left with a sizeable volume defect, scarring and often radiation damage.

"Given that there is no widely accepted reconstructive option available today for partial mastectomy patients, this procedure could well address this substantial unmet need and help complete the overall cancer treatment," said Marc H. Hedrick, president of Cytori.

About the RESTORE Procedure

During the RESTORE Procedure, fat is taken from the patient's stomach, hips, thighs, or other areas by liposuction. Some of the tissue is processed in Cytori's Celution? system to extract the patient's own regenerative cells which occur naturally inside the tissue. The extracted cells are then combined with the remaining fat tissue, forming an ADRC-enriched fat graft that is injected into the breast to restore its natural look and feel. In addition to providing an entirely natural reconstruction, the procedure is minimally invasive with the potential to reduce scarring. The Celution? system is not commercially available in the United States.

About the RESTORE-2 Trial

RESTORE-2 is a 71 patient European post-marketing trial primarily intended to measure patient and physician satisfaction in reconstructing the breast utilizing the Celution? system. The trial took place at the following sites: Hospital General Universitario Gregorio Mara??n in Madrid, Spain, Glasgow Royal Infirmary in Glasgow, Scotland, KU Leuven University Hospitals in Leuven, Belgium, Azienda Ospedaliero Universitaria Careggi in Florence, Italy, Instituto Valenciano Oncolog?a in Valencia, Spain, Norfolk and Norwich University Hospital in Norwich, England, and Jules Bordet Institute of Cancer in Brussels, Belgium.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
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Cytori Therapeutics. "Publication Of Cytori Breast Reconstruction Cell Therapy Trial Results." Medical News Today. MediLexicon, Intl., 21 Mar. 2012. Web.
8 Jun. 2012. APA

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Plastic Surgery Really Does Make People Look Younger

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Academic Journal
Main Category: Cosmetic Medicine / Plastic Surgery
Article Date: 22 Feb 2012 - 0:00 PST Current ratings for:
'Plastic Surgery Really Does Make People Look Younger'
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Plastic surgery seems to make people look about 8.9 years younger than their actual age, researchers from the University of Toronto and NorthShore University Health System reported in Archives of Facial Plastic Surgery.

Jeremy P. Warner, M.D., and team set out to determine how much younger esthetic facial surgical procedures made people look, in order to measure surgical success.

They gathered data on 60 patients who had all undergone facial plastic surgeries. They were aged between 45 and 72 years. The patients were divided into three groups: Face and neck lift groupFace and neck lift and eyelid work (blepharoplasty) groupEyelid work, and face, neck and forehead liftsForty medical students were asked to guess the age of people shown to them in photographs. They looked at pictures of patients before and after surgery.

The researchers found that: Photographs taken before surgery - students guessed they were 1.7 years younger than they actually were (average)Photographs taken after surgery - overall (all three groups), students guessed they were 8.9 years younger than they actually wereFace and neck lift group - 5.7 year change in perceived ageFace and neck lift and eyelid work - 7.5 years change in perceived ageEyelid work, and face, neck and forehead lifts - 8.5 year change in perceived ageThe medical students were fairly similar in how they perceived people's ages.

The authors explained that their study differs from previous ones in that it quantified how much younger the medical students thought the people in the photographs were after undergoing surgery. They added that the more facial surgeries people do, the younger their perceived age becomes.

The authors wrote:

"This effect is more substantial when the number of surgical procedures is increased, an effect unrelated to the preoperative age of a patient and unaffected by other variables that we investigated. The ability to perceive age correctly is accurate and consistent."

Written by Christian Nordqvist
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today

Visit our cosmetic medicine / plastic surgery section for the latest news on this subject. "Perceived Age Change After Aesthetic Facial Surgical Procedures - Quantifying Outcomes of Aging Face Surgery"
Nitin Chauhan, MD, FRCSC; Jeremy P. Warner, MD; Peter A. Adamson, MD, FRCSC
Arch Facial Plast Surg. Published online February 20, 2012. doi: 10.1001/archfacial.2011.1561 Please use one of the following formats to cite this article in your essay, paper or report:

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Christian Nordqvist. "Plastic Surgery Really Does Make People Look Younger." Medical News Today. MediLexicon, Intl., 22 Feb. 2012. Web.
8 Jun. 2012. APA

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posted by Diana on 30 Apr 2012 at 12:32 pm

In fact, unfortunately, in some cases, from certain age, the diet or yoga do not help to eliminate weight or some other kind of problem! That's why I used plastic surgery to get rid of my belly! The result is great. The importaint thing is to do it in a serious clinic. For example me, I asked my friends, and one of them recommended a clinic in Paris. I was pleasantly surprised by the prices, and had a feeling to come on vacation but not to be operated.

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posted by carolina on 22 Feb 2012 at 8:57 am

i think that the age of people is more exactly seen not in a picture but in real presence, when people talk an make gestures like smiling. i think people with plastic surgery look younger when they are still, like in a picture, but not when they make all the natural gestures people make when talking, getting angry, smiling, etc.

(sorry for my english, i?m from Per?)

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Plastic Surgery - Enormous Increase In Uptake By Younger Women

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Main Category: Cosmetic Medicine / Plastic Surgery
Also Included In: Women's Health / Gynecology
Article Date: 16 Mar 2012 - 7:00 PDT Current ratings for:
'Plastic Surgery - Enormous Increase In Uptake By Younger Women'
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Professor Laurence Kirwan, one of the world's leading plastic surgeons, who has appeared on BBC Breakfast to comment on the PIP breast implant scandal and who wrote in the Mail on Sunday (British newspaper) how cosmetic surgery can prolong life, has said that more and more young women between the ages of 35 and 40 years have cosmetic surgery.

Professor Kirwan says that the number of women between 35 and 40 years who have cosmetic surgery every single year for 5 years has risen by 5%.

He says that most young women opt for 'liquid lifts', injections of facial fillers, which typically consist of hyaluronic acid, a gel-like substance that occurs naturally in the skin and helps retain moisture to make cheeks look fuller and lift sagging jaws. The 'liquid lifts' together with Botox freeze the muscles to lift drooping eyebrows by interfering with nerve transmission.

Younger women tend to choose a short-scar facelift (SSFL), whereby the skin is pulled upwards and then pulled back over the bony structures of the face, whilst fat pads that have dropped with aging are repositioned into their proper place. This new and nonintrusive procedure only has a maximum two-week down time costs about ?10,000 ($16,000) with results lasting for as long as 10 years.

Kirwan says:

"This is a miracle treatment for many young women wanting to cut off the effects of ageing at the pass. They don't want to wait until they look older. They strike in advance. It is the perfect choice for those seeking to turn back the clock. It redefines the lower face, jawline and upper neck. It lifts the mid-face and the only visible sign it leaves is a 0.4in scar tucked into the crease where the ear joins the cheek. The rest of the incisions are hidden in the hairline and the back of the ear."

Many younger women also choose mini-facelifts, like the one-stitch facelift whereby the surgeon removes a semi-circle of skin at the hairline at the top of the ear, which pulls up the skin and tissues over the cheeks as the wound is stitched together. This 30-minute procedure is performed under local anesthetic and costs about ?2,000 ($3,200) but only lasts 1 year.

This procedure instantly 'refreshes' a woman's look and because it only leaves a small scar hidden in the hairline, nobody will ever be any the wiser.

Professor Kirwan, who is a member of the British Association of Aesthetic Plastic Surgeons, explains:

"Surgical techniques have become significantly more refined in the past decade and the surgery is tailored to the individual while retaining a very natural result."

According to Kirwan, the demand for plastic surgery has increased by 250% in two years, with facelifts currently being amongst the top three procedures at his surgery.

The British Association of Aesthetic Plastic Surgeons published new figures that show a 4.7% to 4,700% rise in demand in 2011 for surgical facelifts performed by their organization members.

"The growing acceptance of Botox and fillers by women under 30 has made the step-up to cosmetic surgery much less scary," explains Kirwan, continuing that younger women recommend cosmetic surgery to their friends, with the result that more and more younger women choose to have surgery.

He says:

"If it's the done thing in the young social circle and the results are fantastic, then this is playing a major part in why so many younger women are opting for cosmetic procedures."

Written by Petra Rattue

View drug information on Botox.
Copyright: Medical News Today
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Petra Rattue. "Plastic Surgery - Enormous Increase In Uptake By Younger Women." Medical News Today. MediLexicon, Intl., 16 Mar. 2012. Web.
8 Jun. 2012. APA

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Male Tummy Tucks Up 15% In UK

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Main Category: Cosmetic Medicine / Plastic Surgery
Also Included In: Men's health;  Women's Health / Gynecology
Article Date: 30 Jan 2012 - 6:00 PST Current ratings for:
'Male Tummy Tucks Up 15% In UK'
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Britons appear to be tightening their belts in more ways than one: 2011 audit figures from the British Association of Aesthetic Plastic Surgeons (BAAPS) revealed on Monday that the number of men undergoing tummy tucks (abdominoplasty) was 15% higher than in 2010.

However, although the percentage rise is large, the numbers are relatively small compared to women: while male tummy tucks rose from 108 to 124, female ones rose from 3,039 in 2010 to 3,251 in 2011 (a rise of 7%).

And the austere financial climate does not appear to have eroded Britons' belief in cosmetic surgery in other areas either. Not one area of cosmetic surgery fell in popularity in the UK last year.

Across the board the number of procedures carried out by BAAPS members in 2011 was 43,069, which is 5.8% higher than in 2010, matching a similar rise as from 2009 to 2010.

Fazel Fatah is a consultant plastic surgeon and the current president of BAAPS. He told the media:

"It is understandable that procedures for the more noticeable areas of the face and body -- such as breast augmentation, rhinoplasty (nose jobs) and eyelid surgery -- continue to prove popular when patients are looking to get the most 'impact' from their surgery to enhance their mental well being and self-confidence."

BAAPS President Elect Rajiv Grover is a consultant plastic surgeon and responsible for the UK national audit. He said:

"The continued popularity of aesthetic plastic surgery even through financially difficult times demonstrates that the public sees real value in the psychological and physical improvement that can be achieved."

Here are some further highlights of the BAAPS 2011 audit: Male surgery continues to account for 10% of all cosmetic surgery procedures.
Male cosmetic surgery procedures rose by 5.6% from 2010 to 2011: (from 4,017 procedures to 4,298).
There was a similar growth in cosmetic surgery procedures for women: they went up by 5.8% from 2010 to 2011 (from 34,413 procedures to 38,771).
Breast augmentation ("boob jobs") continues to hold its number one place as the most common procedure of all (nearly twice as many of these as the next most popular), and holds its steady growth of 6.2% from 9,418 procedures in 2010 to 10,003 in 2011.
Gynaecomastia ops ("man boob" reduction) were the second most common procedure in men in 2011, as they were in 2010. However, they rose by 7% from 741 in 2010 to 790 in 2011.
Another area of male cosmetic surgery rose even more than this: male liposuction went up by 8% from 473 in 2010 to 511 in 2011.Fatah said the sharp rise in tummy tucks and liposuction should come as no surprise, because more patients are having obesity treatments like gastric bands.

"These patients are usually left with a lot of loose skin that causes physical problems and unsightly body contour which can only be addressed by surgery," said Fatah.

Grover said another reason for the continuing rise in popularity of cosmetic surgery could be because techniques have advanced, so it's "harder to tell" if someone has had it: "they may just look well-rested, or refreshed".

Speculating on other reasons for the rise in procedures carried out by BAAPs surgeons, Grover said, whether it is "because of the recent implant scare or a backlash against some 'lunchtime' non-surgical treatments that don't deliver what they promise", it was reassuring that more patients appear to be "doing their homework" and going on more than just price, to select their cosmetic surgeon.

Click here for more figures from the BAAPS annual audit.

Written by Catharine Paddock PhD
Copyright: Medical News Today
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Catharine Paddock PhD. "Male Tummy Tucks Up 15% In UK." Medical News Today. MediLexicon, Intl., 30 Jan. 2012. Web.
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Cleft Lip/Palate Cause Much More Than Cosmetic Problems

Main Category: Cleft Palate
Also Included In: Pediatrics / Children's Health;  Cosmetic Medicine / Plastic Surgery
Article Date: 26 May 2012 - 0:00 PDT Current ratings for:
'Cleft Lip/Palate Cause Much More Than Cosmetic Problems'
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Children born with cleft lip, cleft palate and other craniofacial disorders face numerous medical challenges beyond appearance.

Patients can face serious airway, feeding, speech and hearing problems, as well as social and psychological challenges, Laura Swibel Rosenthal, MD, of Loyola University Medical Center and colleagues write in the June 2012 issue of Otolaryngologic Clinics of North America.

"The management of patients with craniofacial syndromes is complex," Rosenthal and colleagues write. "Otolaryngologic [ear-nose-throat] evaluation is of paramount importance in providing adequate care for this patient population."

About 1 in 600 babies in the United States is born with a cleft lip and/or cleft palate, according to the Cleft Palate Foundation. The defect can range from a small notch in the lip to a grove that runs into the roof of the mouth. It can occur in isolation or in combination with other craniofacial birth defects. (A craniofacial disorder refers to an abnormality of the face and/or head.)

The first step in managing craniofacial patients is ensuring a safe airway. There's also a great potential for nasal obstruction and sleep apnea. And patients are at increased risk of developing upper airway problems such as sinusitis, laryngitis and rhinitis.

Hearing loss is common and often progressive. Thus, in addition to receiving standard newborn hearing screening, craniofacial patients should continue to receive periodic hearing tests, Rosenthal and colleagues write.

Craniofacial patients typically require several corrective surgeries, performed in staged fashion. Surgeons and anesthesiologists should be aware of the potential challenges these patients may have with general anesthesia.

The authors recommend a multidisciplinary approach, beginning with genetic counseling to determine the cause of the malformation, to inform parents about what to expect and to learn about the implications for other family members.

In addition to otolaryngologists, other specialists who typically care for craniofacial patients include pulmonologists, gastroenterologists, dentists and orthodontists. Depending on the congenital condition, a patient also may see pediatric specialists, such as cardiologists, ophthalmologists, neurosurgeons, endocrinologists, urologists, nephrologists and orthopaedic surgeons.

Most patients also need additional support services, including case management (social work), psychology or psychiatry, speech pathology, physical therapy, occupational therapy and other educational services.

The authors detail the management of major conditions associated with craniofacial disorders, including Apert syndrome, Crouzon syndrome, CHARGE syndrome, chromosome-22 and 22q11.2 deletion syndromes, DiGeorge syndrome, velocardiofacial syndrome (VCFS), Opitz G/BBB syndrome, congenital nasal pyriform aperture stenosis, Moebius syndrome, mandibulofacial dysostosis syndromes, oculoauricular-vertebral spectrum (OAVS), Goldenhar syndrome and Stickler syndrome.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our cleft palate section for the latest news on this subject. Rosenthal is an assistant professor in the Departments of Otolaryngology and Pediatrics of Loyola University Chicago Stritch School of Medicine. Her special interests include cleft lip and palate, breathing difficulties, facial lesions, nasal/sinus problems, neck masses, pediatric ear, nose and throat, special-needs children and speech delay.
Co-authors are Nadieska Caballero, MD, of Loyola's Department of Otolaryngology and Amelia Drake, MD, of the University of North Carolina Hospital.
Loyola University Health System Please use one of the following formats to cite this article in your essay, paper or report:

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posted by Dr. J on 26 May 2012 at 7:11 am

As a DMD MD Facial surgeon I have studied craniofacial surgery in France and worked with patients here in the US! I noticed the absence of the mention of both Plastic and Oral Maxillofacial surgeons from this article about ENT doctors. Don't you think it's time to put the patient ahead of hospital politics and truly have that multi-disciplinary approach rather than lip service to lip and other facial deformities?

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'Cleft Lip/Palate Cause Much More Than Cosmetic Problems'

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New Research Suggests PIP Implant Failures Significantly Higher Than Previously Thought

Main Category: Cosmetic Medicine / Plastic Surgery
Also Included In: Women's Health / Gynecology
Article Date: 18 Apr 2012 - 0:00 PDT Current ratings for:
'New Research Suggests PIP Implant Failures Significantly Higher Than Previously Thought'
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New research published in the Journal of Plastic, Reconstructive and Aesthetic Surgery suggests that the failure rate of silicone breast implants manufactured by Poly Implant Prosth?se (PIP) could be as high as 33.8%.

Patients who received PIP implants either for primary or secondary breast augmentation, between January 2000 and August 2005, were studied to determine implant failure rate and other complications. Results found that 7 to 12 years after implantation the failure rate for PIP implants is in the region of 15.9-.8%.

"Previous studies have typically reported failure rates of between 2% and 5% and these estimates have been based on secondary data. In this study, all participants were scanned by ultrasound, which provides conclusive indication of rupture, rather than clinical examination which is typically used. Most previous studies were based on multiple surgeon, multiple technique, with a relatively small number of patients and shorter follow up time span," commented Mr. Jan Stanek, lead author of the study.

Concerns about the durability of PIP silicone breast implants have been expressed for several years prior to their formal withdrawal from the UK market in March 2010. Although precise details of what elements were at fault remain unclear, concerns have been raised about both the elastomer (the outer cover of the implant) and the filler gel.

In this study PIP implants were used by the plastic surgeon for both primary and secondary breast augmentation. A database of patients was constructed and each patient was offered a free consultation and referral for ultrasound scan. Chief outcome measures included secondary surgery, implant rupture rate and time to rupture.

453 patients with PIP devices were identified. Of this number, 30 had already undergone implant exchange for a variety of reasons. 180 (39.7%) could not be contacted and 19 had undergone implant removal elsewhere. Of those who could be contacted, 47 declined consultation as they had no concerns. 97 had neither clinical signs nor radiographic evidence of implant rupture and elected to remain under regular review. At the time of writing, 38 had undergone implant exchange after ultrasonographic indication of rupture.

Based on these results, if the group of non-responders had no ruptures, the overall rupture rate would be 15.9%. However, it the non-responders had the same rupture rate as those examined in the study, the overall rupture rate would be 33.8%.

Mr. Stanek indicates that all PIP implants, due to the high rupture rate and uncertainty about the nature of the silicone gel, may need to be removed. Those patients with ruptured implants will have to have them removed; those with no evidence of rupture will need to be monitored on a regular basis. Further research into the nature of the elastomer and gel filler will determine whether all PIP implants should be explanted in the future.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our cosmetic medicine / plastic surgery section for the latest news on this subject. This article is "The PIP mammary prosthesis: A product recall study" M.G. Berry and Jan J. Stanek (DOI: 10.1016/j.bjps.2012.02.019); in press, ahead of print in Journal of Plastic, Reconstructive and Aesthetic Surgery, published by Elsevier.
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PiP Breast Implant Scandal, 7000 More Women May Need Replacement Or Removal UK

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Main Category: Cosmetic Medicine / Plastic Surgery
Article Date: 15 Mar 2012 - 14:00 PDT Current ratings for:
'PiP Breast Implant Scandal, 7000 More Women May Need Replacement Or Removal UK'
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The UK Department of Health has issued an update on PiP breast implants scandal which struck in late 2011. Authorities have identified an additional 7,000 women in the UK that may be in need to replacement or removal of their implants, and have confirmed this should be covered under the same NHS arrangements made earlier in the year.

The additional patients have been identified from those who had surgery before 2011, where previously, the French Authorities who first investigated their local company, believed only those implants after 2001 were suspected of containing unauthorised silicone gel.

It is generally recommended that implants are replaced every ten years, so many of these women may have already elected to replace their implants, or done so under NHS care. The NHS Medical Director, Professor Sir Bruce Keogh, continues to advise that there is not enough evidence to recommend routine removal of PiP breast implants They state on their website that :

"However, we have always recommended that if women are concerned they should speak to their surgeon or GP. The NHS will support removal of PIP implants if, after this consultation, the patient still has concerns and with her doctor she decides that it is right to do so. The NHS will replace the implants if the original operation was done by the NHS. We expect the private sector to do the same for their patients.

We believe that private providers have a duty to take steps to provide appropriate after-care to patients they have treated. If a clinic that implanted PiP implants no longer exists or refuses to care for their patient - where that patient is entitled to NHS services, the NHS will support the removal of PiP implants where clinically necessary. All women should be offered the same care, whether they had their implants before or after 2001."

Health Secretary Andrew Lansley said:

"The French regulator has confirmed this week that more women may be affected by the criminal activity of the French breast implant manufacturer PiP. These women are the victims of a fraudulent company and I know this situation is causing a huge amount of anxiety. I want to reassure those affected by the news today that they will be provided with all the help they need from the NHS.

We are still working to get private clinics to live up to their responsibilities and look after their patients. Our commitment is to ensure support for all women from the NHS if needed; we will continue to press for the same standard of care or redress from private providers."

Professor Dame Sally Davies, the Chief Medical Officer said:

"The expert group advises that there is no evidence to suggest that every woman with a PiP implant should have them removed. But we know this is a worrying time for them and want them to be able to see a GP or specialist to get reassurance and have them removed if necessary. All women who had the implants put in on the NHS will be able to have them removed and replaced by the NHS. We expect private clinics to offer their patients the same care. If they refuse, the NHS will provide advice, a scan and, if necessary, remove the implants.

Private patients will not, however, be able to have their implants replaced on the NHS unless this is clinically necessary. We will be placing adverts in the weekend papers again to inform all women with PiP implants about the advice from the experts and how they can get help if they are concerned. I have also written to GPs today to remind them that we want them to help women with PiP implants."

The Department of Health is advising women with PiP implants to take three steps to reassure themselves. The steps are to:
Find out if they have PiP implants by checking their medical notes. This information can be accessed for free from clinics or through GPs. Most women who had PiP implants on the NHS should already have received a letter ... anyone who received an implant between 1997 and 2000 will be contacted in the near future.
Speak to their GP or surgeon. Women who had PiP implants on the NHS should speak to their specialist or GP and women who had them done privately should speak to their clinic.
Agree what's best for you. Women should get advice on whether or not they need a scan then discuss appropriate action with their doctor.Patients have been told that the NHS will do removals for free if the original surgery was done on the NHS. However, if the original operation was performed in a private clinic, the patient will need to speak to their clinic to see if they will replace them for free.

Further information is available at http://www.nhs.uk/Conditions/Breast-implants/Pages/PIP.

The Chief Medical Officer has written again to all GPs to set out what they should do if a private patient with PiP implants asks for their help, and to inform them about the change in advice from the French authorities. The letter is available on the NHS Choices website at http://www.nhs.uk

Written by Rupert Shepherd
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PIP Breast Implants Unsafe, Say German Authorities

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Main Category: Cosmetic Medicine / Plastic Surgery
Article Date: 31 Jan 2012 - 10:00 PST Current ratings for:
'PIP Breast Implants Unsafe, Say German Authorities'
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German authorities at the BfArM Institute have officially informed the International Society for Aesthetic Plastic Surgery (ISAPS) that the former GfE Medizintechnik GmbH in Germany sold breast implants under the name TiBREEZE from September 2003 to August 2004, which were manufactured with PIP components.

GfE Medizintechnik GmbH was coating silicone implants with a titanium layer and sending them to PIP in France to be filled with their silicone gel, which consisted of the same composition of industrial grade silicone that PIP and Rofil implants were filled with since 2001. The German authorities at the BfArM Institute therefore amended the recommendation to remove PIP and Rofil implants they made earlier this month to also include TiBREEZE implants as a measure of precaution, even in the absence of any symptoms.

GfE's company successor informed ISAPS that 728 implants were produced during the period of the former company's affiliation with PIP. The majority of TiBREEZE implants were sold and used in 280 patients in Germany. Other countries that bought the implants include Austria, Belgium, England, Finland, Italy, Lichtenstein, Switzerland and South Africa. It is thought that a total of 400 patients are affected.

Dr. Dirk Richter (Germany), Chair of ISAPS' Patient Safety Committee declared:

"as there are no studies yet available to prove the safety of industrial grade silicone in the human body, ISAPS supports the French and German authorities' recommendations and encourages all women with TiBREEZE, PIP or Rofil breast implants produced after 2001, to check with a specialized plastic surgeon to discuss removal of the implants."

The International Society of Aesthetic Plastic Surgery is the largest international society of individual board certified, or equivalent aesthetic plastic surgeons. It was founded forty-one years ago and counts 2,140 members in 93 countries. To join the society, surgeons must undergo a strict application process to determine their qualifications. ISAPS mission is to continue educating plastic surgeons in the latest techniques in the field of aesthetic plastic surgery and medicine and to promote patient safety.

All ISAPS members are listed on the website.

Written by Petra Rattue
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posted by PIP breast implant claims on 20 Feb 2012 at 2:40 pm

Sirs

I agree with the statement. I am a UK Solicitor taking action on behalf of women with PIP breast implants. I am disappointed with the UK stance and trust this will change otherwise the Courts will have to decide.

| post followup | alert a moderator |


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Visible Signs Of Aging Improved By Pycnogenol (French Maritime Pine Bark Extract) In New Study

Main Category: Cosmetic Medicine / Plastic Surgery
Also Included In: Seniors / Aging;  Dermatology;  Women's Health / Gynecology
Article Date: 26 Jan 2012 - 1:00 PST Current ratings for:
'Visible Signs Of Aging Improved By Pycnogenol (French Maritime Pine Bark Extract) In New Study'
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Human skin is the body's first line of defense and often mirrors the health, nutritional status and age of a person. Over time, skin shows signs of aging due to the gradual breakdown of collagen and elastin. However, skin can be rebuilt and made healthier no matter one's age. Natural supplement Pycnogenol? (pic-noj-en-all), an antioxidant plant extract from the bark of the French maritime pine tree, was found to improve skin hydration and elasticity in women in a clinical trial published this month in Skin Pharmacology and Physiology.

The study was conducted at the Leibniz Research Institute for Environmental Medicine (IUF) in Dusseldorf, Germany and examined 20 healthy women, aged 55 - 68 years. Participants were given 75 mg of Pycnogenol? per day, over a period of 12 weeks. Skin hydration, skin elasticity and skin fatigue were assessed by non-invasive biophysical methods at trial start and after six and 12 weeks. In addition, at the beginning and again after 12 weeks of Pycnogenol? supplementation, each time, a biopsy was obtained to assess gene expression of HAS-1 and COL1A1 and COL1A2. The study found that: Pycnogenol? elevated COL1A1 by 29 percent and COL1A2 by 41 percent and increased hyaluronic acid production in skin by 44 percent Pycnogenol? enhanced skin elasticity by 25 percent, in addition to skin hydration by eight percent, and was especially noticeable in women who had dry skin from the start, with an increase of 21 percent Pycnogenol? decreased skin fatigue considerably Pycnogenol? reduced skin wrinkles by three percent and increased skin smoothness by six percent "To date, Pycnogenol? is the only natural supplement that stimulates hyaluronic acid production in human skin. And, we are encouraged by the molecular evidence confirmed in this study that shows nutritional supplementation with Pycnogenol? benefits human skin," explains Dr. Jean Krutmann, the lead researcher from the Leibniz Research Institute in Dusseldorf, Germany.

Study results confirmed Pycnogenol? improved skin at a physiological and molecular level. Pycnogenol? increased hyaluronic acid in women by 44 percent after 12 weeks of supplementation. Hyaluronic acid binds large quantities of water in the skin and in other tissues, such as cartilage. An increased amount of hyaluronic acid explains the increased skin hydration, higher elasticity and overall smoother skin appearance found in women taking Pycnogenol?.

"This exciting and technically advanced investigation with women representing actual consumer profiles greatly supports our efforts for targeting the skin beauty category for both dietary supplements and functional foods," says Victor Ferrari, CEO of Horphag Research, exclusive worldwide suppliers of Pycnogenol?, who welcomes the publication.

According to Ferrari, beauty from within has been a driver in Horphag's business for the last several years, with Asian markets providing numerous Pycnogenol? products in the skincare field. This study joins a sizable and largely expanding portfolio of already established skin research on Pycnogenol?. It confirms previous indications that Pycnogenol? improves human skin conditions, including promoting glowing skin and reducing the appearance of over-pigmentation and skin inflammation, resulting in a more even complexion.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
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Physicists Devise Method For Building Artificial Tissue

Main Category: Pharma Industry / Biotech Industry
Also Included In: Cosmetic Medicine / Plastic Surgery
Article Date: 30 May 2012 - 0:00 PDT Current ratings for:
'Physicists Devise Method For Building Artificial Tissue'
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New York University physicists have developed a method that models biological cell-to-cell adhesion that could also have industrial applications.

This system, created in the laboratory of Jasna Brujic, an assistant professor in NYU's Department of Physics and part of its Center for Soft Matter Research, is an oil-in-water solution whose surface properties reproduce those found on biological cells. Specifically, adhesion between compressed oil droplets mimics the mechanical properties of tissues and opens the path to numerous practical applications, ranging from biocompatible cosmetics to artificial tissue engineering.

Their method is described in the journal the Proceedings of the National Academy of Sciences.

Previously, Bruji?'s laboratory has determined how spheres pack and devised methods for manipulating the packing process. In this PNAS study, Bruji? and her research team sought to create a method that would address the role of packing in tissues from the point of view of how mechanical forces affect protein-protein adhesion between cells.

In biology, cell-to-cell adhesion is crucial to the integrity of tissue structure - cells must come together and stick in order to ensure tissue cohesion. However, the daunting complexity of biological systems has long prevented their description using general theoretical concepts taken from the physical sciences. For this reason, the research team designed an original biomimetic solution, or emulsion, that reproduces the main features of cell-to-cell adhesion in tissues.

Emulsions form the basis for a range of consumer products, including butter, ice cream, and milk. In addition, the emulsion in the PNAS study is tuned to match the attractive and repulsive interactions that govern adhesion between cells. The experimental conditions reveal the circumstances under which pushing forces are necessary to create adhesion.

By varying the amount of force by which the droplets of oil were compressed by centrifugation and the amount of salt added to this solution, the NYU team was able to isolate the optimal conditions for cell-to-cell adhesion. Screening electrostatic charges by the addition of salt and compressing the droplets by force enhances protein-protein interactions on the droplet surfaces. This leads to adhesion between contacting droplets covering all the interfaces, just as in the case of biological tissues.

Their results, which matched the researchers' theoretical modeling of the process, offer a method for manipulating force and pressure in order to bind emulsions. This serves as a starting point for enriching a range of consumer products, by reconfiguring their molecular make-up to enhance consistency and function, and for improving pharmaceuticals, by bolstering the delivery of therapeutic molecules to the blood stream.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our pharma industry / biotech industry section for the latest news on this subject. The study's other authors were Lea-Laetitia Pontani, a postdoctoral research scientist, and Ivane Jorjadze, a graduate student, both from NYU's Department of Physics and the Center for Soft Matter Research, as well as Virgile Viasnoff, an Associate Professor at the National University of Singapore and the French research institute, CNRS/ESPCI.
The research was performed in the NYU Materials Research Science and Engineering Center (MRSEC), which is supported by the National Science Foundation.
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Tips For African-American Patients To Reduce Their Risk Of Developing A Hair Or Scalp Disease

Main Category: Dermatology
Also Included In: Cosmetic Medicine / Plastic Surgery;  Epilepsy
Article Date: 21 Mar 2012 - 0:00 PDT Current ratings for:
'Tips For African-American Patients To Reduce Their Risk Of Developing A Hair Or Scalp Disease'
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Styling practices can lead to serious hair and scalp diseases for some African Americans, says Henry Ford Hospital dermatologist Diane Jackson-Richards, M.D.

"Hair is an extremely important aspect of an African-American woman's appearance," says Dr. Jackson-Richards, director of Henry Ford's Multicultural Dermatology Clinic. "Yet, many women who have a hair or scalp disease do not feel their physician takes them seriously. Physicians should become more familiar with the culturally accepted treatments for these diseases."

Dr. Jackson-Richards says proper hair care can help prevent the onset of such diseases like seborrheic dermatitis and alopecia, and that dermatologists need to become more sensitive to the hair and scalp plights of African Americans.

Dr. Jackson-Richards will discuss these issues Monday during a presentation of "Hair Disease and the African-American Patient" at the annual American Academy of Dermatology conference in San Diego.

Little research has been done about the prevalence and causes of hair and scalp diseases in African Americans. Dr. Jackson-Richards says understanding the unique physiologic characteristics of African textured hair - for example, it grows slower and has a lower hair density than other ethnic groups - will assist dermatologists in prescribing treatment options.

African-American women are known to shampoo their hair less frequently than other ethnic groups, and an estimated 80 percent of them use chemical relaxers. Frequent use of blow dryers and hot combs, combined with popular hair styles like hair weaves, braids and dreadlocks, add physical stress to the hair and contribute to scalp diseases like alopecia, or hair loss.

"Hair loss is the fifth most common condition cited by patients when they visit their dermatologist," Dr. Jackson-Richards says.

Dr. Jackson-Richards suggests these grooming tips for patients to reduce their risk of developing a hair or scalp disease: Wash hair weekly with a moisturizing shampoo and conditioner. Allow two weeks between relaxing and coloring. Limit use of blow dryers and hot combs and other heated hair styling products to once a week. Wash braids or dreadlocks every two weeks. Avoid wearing braids too tightly; don't wear longer than three months. To detangle hair, use a wide tooth comb while conditioner is still in the hair. Use natural hair oils with jojoba, olive, shea or coconut oils.Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
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Plastic Surgeries Continue To Grow, Despite Sluggish Economy, USA

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Main Category: Cosmetic Medicine / Plastic Surgery
Article Date: 11 Feb 2012 - 10:00 PST Current ratings for:
'Plastic Surgeries Continue To Grow, Despite Sluggish Economy, USA'
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13.8 million plastic surgery procedures were performed in 2011, a 5% increase on the year before, according to a new report issued by the American Society of Plastic Surgeons (ASPS). The authors added that by the end of 2011, the number of total plastic surgeries had grown for 24 consecutive months. These figures include both minimally-invasive and surgical procedures.

The ASPS informs that 5.5 additional reconstructive procedures were carried out in 2011, also a 5% increase on the previous year.

ASPS President Malcolm Z. Roth, MD., said:

"While the rate of economic recovery in the U.S. is still uncertain, 2011 proved to be a good year for plastic surgery. Consumer confidence was up, auto sales rose 10 percent, so it is not surprising that we would also see increased demand for plastic surgery procedures."
1.6 cosmetic procedures were performed in 2011, a 2% increase over the previous year. Below are some details on the top five in 2011 compared to 2010: Breast implant - 307,000. A rise of 4%Rhinoplasty (nose job) - 244,000. A reduction of 3%Liposuction - 205,000. A rise of 1%Blepharoplasty (eyelid surgery) - 196,000. A drop of 6%Rhytidectomy (facelift) - 119,00. A rise of 5%Facelifts replaced tummy tucks for fifth place last year; the first time that procedure was among the top five since 2004.

Chin augmentations, also known as "chin implants", rose 71% to 21,000 procedures in 2011.

Lip enhancement, also known as "lip augmentation" increased by 49% to 25,000 procedures carried out last year.

Dr. Roth said:

"We are seeing notable increases in surgical procedures, such as facelifts, that reflect the demands of an aging boomer population. However, the overall growth in cosmetic procedures is being primarily driven by a substantial rise in minimally-invasive procedures."
There were 12.2 million minimally-invasive procedures last year, a rise of 6%. Below are some details of the top five most popular in 2011: Botulinum toxin type A - 5.7 million. A rise of 5%Soft tissue filler - 1.9 million. A rise of 7%Chemical peel - 1.1 million. A fall of 3%Laser hair removal - 1.1 million. A rise of 15%Microdermabrasion - 900,000. A rise of 9%Among the increases that stood out in 2011 for minimally-invasive procedures were soft tissue fillers, such as calcium hydroxylapatite (Radiesse?), fat injections, and hyaluronic acid (Restylane?, Juvederm Ultra?). Below are some details on totals for 2011, and how they compared to the previous year: Hylauronic acid procedures - over 1.3 million. A rise of 9%Calcium hydroxylapatite procedures - 286,000. A rise of 36%Fat injections - 68,000. A rise of 19%This type of surgery, which aims to improve the appearance of abnormal structures, as well as function, increased by 5% in 2011 compared to the previous year. Below are details on the top five reconstructive plastic surgery procedures: Removing a tumor - 4.2 million. A rise of 3%Laceration repair - 303,000. A drop of 15%Maxillofacial surgery - 195,000. A rise of 125%Scar revision - 175,000. A rise of 9%Hand surgery - 120,000. A rise of 13%There were 96,000 breast reconstruction procedures in 2011, a rise of 3% compared to the previous year.

Dr. Roth said:

"While insurance coverage for breast reconstruction is mandated by law, continued strides to provide coverage for other reconstructive procedures has contributed, in part, to the sizable gain that we are seeing with these procedures. Reconstructive surgery is a critical pillar of the specialty, and it is encouraging to see that increasing numbers of patients entrust board-certified plastic surgeons to reconstruct their bodies after disease or trauma."

Written by Christian Nordqvist
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Head And Facial Abnormal Features Repair Themselves

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Main Category: Dermatology
Also Included In: Cosmetic Medicine / Plastic Surgery
Article Date: 02 May 2012 - 9:00 PDT Current ratings for:
'Head And Facial Abnormal Features Repair Themselves'
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A report in the May issue of the journal Developmental Dynamics reveals that biologists from the Tufts University have, for the first time, discovered a "self-correcting" mechanism by which developing organisms recognize and repair head and facial abnormalities.

This is the first time that this kind of flexible, corrective process has been rigorously analyzed through mathematical modeling.

The study demonstrates that developing organisms are not genetically "hard-wired", but that the process is, instead, more flexible and robust. By using a tadpole model with a set of pre-determined cell movements that result in normal facial features, they demonstrated that cell groups can measure their shape and position in relationship to other organs, as well as performing the required movements and remodeling functions in order to compensate for important abnormalities in patterns.

Senior researcher, Michael Levin, Ph.D., director of the Center for Regenerative and Developmental Biology in Tufts University's School of Arts and Sciences explained:

"A big question has always been, how do complex shapes like the face or the whole embryo put themselves together? We have found that when we created defects in the face experimentally, facial structures move around in various ways and mostly end up in their correct positions. This suggests that what the genome encodes ultimately is a set of dynamic, flexible behaviors by which the cells are able to make adjustments to build specific complex structures. If we could learn how to bioengineer systems that reliably self-assembled and repaired deviations from the desired target shape, regenerative medicine, robotics, and even space exploration would be transformed."

Earlier research had discovered self-correcting mechanisms in other embryonic processes, yet never in the face. These mechanisms had not been analyzed mathematically to shed a light onto the corrective process' precise dynamics.

Leading researcher, Laura Vandenberg, Ph.D., a post-doctoral associate at the Center for Regenerative and Developmental Biology said:

"What was missing from previous studies - and to our knowledge had never been done in an animal model - was to precisely track those changes over time and quantitatively compare them."

An analysis like this is vital for gaining insight into what information is being generated and manipulated so that a complex structure can rearrange and repair itself.

The team of biologists made one side of the embryos abnormal by injecting specific mRNA into one cell at the two-cell stage of development, which induced craniofacial defects in Xenopus frog embryos.

They then characterized changes of the craniofacial structures in terms of their shape and position, including jaws, eyes, branchial arches, otic capsules and olfactory pits by performing a 'geometric morphometric analysis' that measures the position of 32 landmarks on tadpoles' top and bottom sides.

By taking images of tadpoles at precise intervals, the researchers observed that the craniofacial abnormalities (perturbations), in particular, in the jaws and branchial arches became less apparent as the tadpoles aged. They also noted that the tadpoles' eye and nose tissue became more normal over time, although they did note various differences in achieving a completely expected shape and position.

In any baby animal it is a normal part of development that facial features change in terms of their shape and position. As the animal gets older, their faces elongate and their eyes, nose and jaws grow in relation to each other, even though the movement is generally fairly marginal.

The team observed, however, that in tadpoles with severe malformation, a major dramatic shift occurred in the facial structures in order to repair those malformations. They stated that it appeared as if the system was able to detect deviations from the normal state and perform corrective actions that would not typically take place.

"We were quite astounded to see that, long before they underwent metamorphosis and became frogs, these tadpoles had normal looking faces. Imagine the implications of an animal with a severe 'birth defect' that, with time alone, can correct that defect."

The biologists state that the findings were consistent with an information exchange process in which a structure triangulates its distance and angle from a stable reference point. They say that although further studies are required, they suggest exchanging 'pings', i.e. signals that contain information between an 'organizing center' like the brain and neural network and individual craniofacial structures.

The researchers highlight the fact that birth defects, such as cleft lips, cleft palate and microphthalmia affect over 1 in 600 births. New approaches of correcting these birth defects that belong to the category of congenital malformations of craniofacial structures could potentially be corrected in humans by conducting further studies at the molecular level, which would shed more light on the "face-fixing" dynamics.

Levin concluded:

"Such understanding would have huge implications not only for repairing birth defects, but also for other areas of systems biology and complexity science. It could help us build hybrid bioengineered systems, for synthetic or regenerative biology, or entirely artificial robotic systems that can repair themselves after damage or reconfigure their own structure to match changing needs in a complex environment."

Written By Petra Rattue
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today

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8 Jun. 2012. APA

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'Head And Facial Abnormal Features Repair Themselves'

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PIP Breast Implants - UK Dept Of Health Response To Expert Report

Editor's Choice
Main Category: Cosmetic Medicine / Plastic Surgery
Article Date: 13 Jan 2012 - 9:00 PST Current ratings for:
'PIP Breast Implants - UK Dept Of Health Response To Expert Report'
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According to the Department of Health, their main concern is the wellbeing of women who have had PiP breast implants. For this reason, an expert group led by Professor Sir Bruce Keogh, NHS Medical Director, has been asked to examine all available data and evidence on PiP breast implants.

The experts concluded that: There is no association with PiP breast implants and cancer Advice given by the MHRA still stands That there is insufficient evidence to recommend routine extraction of PiP breast implants. However, the group explains that these implants should have never been implanted in women in the first place, as they are made up of non-medical grade silicone. The Department of Health knows that this data will be a worrying for women who have PiP implants. Those who performed the implantations should properly support these women.

Patients with concerns regarding this issue should talk to their GP (general practitioner, primary care physician), or surgeon.

If the woman still has concerns after consulting with her doctor and decides to remove the implants, the NHS will support the removal and replace the implants if the original breast implants was done by the NHS.

The Department of Health expects that those in the private sector do the same for their patients, as private providers have a responsibility to provide appropriate after-care to individuals they have treated as they have legal obligations to their patients.

The NHS will offer a package of care for its patients, and The Department of Health expects the private sector to do the same.

The NHS offer is: The NHS will contact all individuals who have received breast implants from the NHS in order to inform them that they have a PIP implant and provide relevant information and advice. The NHS will provide information free of charge should patients seek information about the make of their implant. Consultations with their GP, or with the surgical team who conducted the original implant, should the women seek clinical advice on the best way forward. Consultations may include imaging scans to determine whether there is any evidence the implant has ruptured. The NHS will remove PIP implants if a woman (with her doctor) decides that it is the right thing to do, and and there is an assessed clinical need. If the original procedure was conducted by the NHS, the NHS will replace the implants. The Department of Health is collaborating with the private sector to make sure an equivalent model of care is provided, as it's unfair for the taxpayer for the NHS to pay the bill.

The NHS will support removal of PiP implants, in line with the guidance above, should the clinic that carried out the operation refuses to care for their patient - where the patient is entitled to NHS services, or no longer exists. The replacement of private cosmetic implants would not be included by any NHS service in that respect. In order to avoid the taxpayer footing the bill, the Government will pursue private clinics with all means at its disposal.

However, the experts are unsure whether the rapture rate is higher for PiP implants than other breast implants.

Studies reveal that if a PiP implant did rupture, there is no risk of dangerous toxins leaking into the body, although the experts are not confident that the manufacturer did not alter the silicone in the implants and therefore cannot rule out that some implants may be toxic.

According to the Department of Health:

"We need to do everything we can to ensure the safety of people having cosmetic surgery.

It's clear from the information we have received from the industry that the safety information it has provided to the regulator is patchy. Without good data, we have no way of knowing when problems arise."

The expert group will analyze the broader issues surrounding the quality of surveillance, data, and enforcement of the sector and sector regulation more generally.

Evidence of providers' compliance with registration requirements are being reviewed by The Care Quality Commission as well as considering a fuller program of inspections.

In addition, the UK and France will continue to collaborate in sharing data and information. Both nations are determined to prevent this situation from happening again. The UK would like to collaborate with countries across the EU in order to fully understand where the failures of this incident fall.

Health Secretary Andrew Lansley explained:

"Throughout the past few weeks, my main concern has been for the safety of and compassion for women who have PIP implants. It has been a worrying time for these women. We have at every stage sought to offer them as much advice and evidence as is available to us.

Our advice remains the same that there is not sufficient evidence to recommend routine removal. We have always recommended that women who are concerned should speak to their surgeon or GP. The NHS will support removal of PIP implants if, after this consultation, the patient still has concerns and with her doctor she decides that it is right to do so.

We believe that private healthcare providers have a moral duty to offer the same service to their patients that we will offer to NHS patients - free information, consultations, scans, and removal if necessary.

Throughout this process we have followed expert advice. The data available to the experts has not been good enough to enable them to give a clear recommendation of the risk posed by PIP implants. We will therefore support women, including removal of the implant, if needed."

Professor Sir Bruce Keogh said:

"The overriding consideration of the group is the safety and compassionate treatment of women with PiP implants.

On the basis of the information we have, we do not think it is necessary to recommend the routine removal of these implants. But we understand that some women will be very concerned so we support the Government's position that the NHS will support removal of PIP implants if the patient has concerns and with her doctor she decides that it is right to do so."

Written by Grace Rattue
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today

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posted by julie on 14 Jan 2012 at 1:24 pm

Every thing on/in my body is original. I thank God every day for what he gave me even if I never win any beauty contests.

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posted by Georgina on 14 Jan 2012 at 8:11 am

ive been to see my doctor and was told they ae not willing to send me for a breast scan or examine me untill they have writen conformation from the private clinic where i had my surgery confirming that i have had surgery on my breasts , Im sure if the doctor had bothered to examine my breast she would have felt the implants and seen the small scares that i have. im really upset with the way the doctor spoke to me has she told me because i had them done private she doesnt see why she should treat me now . I told her that i thought it was her place to treat me has im not asking her to take the implants out but just check that they are ok , I also told her that i had symptoms of the implants leeking and she never asked me what my symptoms are. Ive now made an appointment to see one of the partners at my doctors surgery and see if i get the same answers.

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'PIP Breast Implants - UK Dept Of Health Response To Expert Report'

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Peliculas Online

Inhibitor Causing Male Pattern Baldness Discovered

Editor's Choice
Academic Journal
Main Category: Cosmetic Medicine / Plastic Surgery
Also Included In: Dermatology
Article Date: 23 Mar 2012 - 1:00 PDT Current ratings for:
'Inhibitor Causing Male Pattern Baldness Discovered'
4 and a half stars4 stars
A study published in Science Translational Medicine, from the University of Pennsylvania, explains that scientists looking for the holy grail in beauty treatment have discovered an abnormal quantity of a protein, called Prostaglandin D2, present in the scalp of bald men, that they think may be responsible for their hair loss.

Their work should lead directly to the creation of new treatments for the most common cause of hair loss in men, known as male pattern baldness. The problem of male pattern baldness is seen to varying degrees in 8 of 10 men under 70 years old. It causes hair follicles to shrink and produce microscopic hairs. These grow for a shorter duration than normal follicles, meaning that follicles just don't replace at the fast enough rate for the loss of normal ones.

The prostaglandin, known as PGD2 and its derivative, 15-dPGJ2, have been shown to inhibit hair growth in both human and animal models. The PGD2-related inhibition is associated with a receptor: GPR44, which is now looking as though it will be a promising therapeutic target for androgenetic alopecia (AGA) in both men and women with hair loss and thinning.

George Cotsarelis, MD, chair and professor of Dermatology, and senior author on the studies, explains how his work is building on a previous study from Penn. University published in the Journal of Clinical Investigation last year :

"Although a different prostaglandin was known to increase hair growth, our findings were unexpected, as prostaglandins haven't been thought about in relation to hair loss, yet it made sense that there was an inhibitor of hair growth, based on our earlier work looking at hair follicle stem cells."

More importantly, and giving hope to millions of bald people everywhere, it appears that the underlying hair follicle stem cells are intact. This seems to suggest that the scalp is either lacking an activator or has been inhibited from creating new follicle growth. In the past, general thinking was that the follicles had died permanently, hence leading baldness treatments have involved using new follicles taken from elsewhere on the scalp.

Researchers write that they took an unbiased approach when searching for possible biological causes of baldness. They looked in scalp tissue from balding and non-bald spots from men with male pattern baldness. They then cross-checked their findings in mouse models, where levels of PGD2 were elevated in bald scalp tissue at levels 3 times greater than what was found in comparative haired scalp of men with androgenetic alopecia.

When PGD2 was added to cultured hair follicles, PGD2-treated hair was significantly shortened, while PGD2's derivative, 15-dPGJ2, completely inhibited hair growth.

Prostaglandins are well understood in their role in many bodily functions. They control cell growth, constrict and dilate smooth muscle tissue, and a different prostaglandin (F2alpha) has been seen to increase hair growth. PGD2 on the other hand, inhibits hair growth.

The researchers also make note that prostaglandins may represent a common pathway shared by both men and women with AGA, although so far, they have only looked at male test results. A topical treatment to target GPR44, will determine whether focusing on prostaglandins will benefit women with AGA as well.

Written by Rupert Shepherd
Copyright: Medical News Today
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8 Jun. 2012. APA

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posted by Dr Rafiq Tareen Pathan on 4 Apr 2012 at 8:25 am

After reading this article , it confirms to someextend that the UVB PHtotherapy used in AGA shows the results as it suppresses the activity of Prostaglandins inhibiting the Hair growth. I do see good results of using the UVB PHOTOTHERAPY withy Minoxidil etc.

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posted by Kaku Kyiamah on 29 Mar 2012 at 2:52 pm

Prostaglandins are produced by polyunsaturated fatty acids, which enter the body when we eat polyunsaturated vegetable oils and unfermented grains. Polyunsaturated fatty acids do no useful work in the body. Prostaglandins have been identified as being involved in many diseases, including the formation of atherosclerotic plaque in heart attacks, cancers, asthma, erectile dysfunction in men, dysmenorrhea (menstrual pains)and inelastic vagina in women. Why eat polyunsaturated vegetable oils (thanks to FDA and AHA) and then get ailments and diseases which are difficult to cure.

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posted by micah on 28 Mar 2012 at 8:13 am

alright, now they need to pump out some medicine to fix it!

I neeeed hair!

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posted by Pete Watkins on 22 Mar 2012 at 3:16 pm

THANK GOD! It is about time we solve this issue. I have been fighting male pattern baldness for several years now (topical and propecia) I hope they fast track this medicine as it would greatly improve my quality of living. I have also written my senator to sponsor legislation that this be "medically necessary" and require insurance companies to provide for free Propecia and Minoxidil!!

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posted by Steve Wood on 22 Mar 2012 at 1:32 pm

You can use Polysorbite 80 on your folicles and reduce the DHT in yout scalp and regrow hair. The FDA dis alowed it years ago, It's safe on inexpensive.Wh oare they protecting?

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'Inhibitor Causing Male Pattern Baldness Discovered'

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